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Osteosclerosis owing to Notch gain of function is solely Rbpj‐dependent

Osteosclerosis is a pathologic bone disease characterized by an increase in bone formation over bone resorption. Genetic factors that contribute to the pathogenesis of this disease are poorly understood. Dysregulation or mutation in many components of the Notch signaling pathway results in a wide ra...

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Detalhes bibliográficos
Main Authors: Tao, Jianning, Chen, Shan, Yang, Tao, Dawson, Brian, Munivez, Elda, Bertin, Terry, Lee, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126919/
https://ncbi.nlm.nih.gov/pubmed/20499347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.115
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