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Alteration of Notch signaling in skeletal development and disease

Notch signaling is an evolutionarily conserved mechanism for specifying and regulating organogenesis and tissue renewal. Human and mouse genetic studies have demonstrated mutations in many components of the Notch signaling pathway that cause skeletal patterning defects. More recently, the in vivo ef...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tao, Jianning, Chen, Shan, Lee, Brendan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952341/
https://ncbi.nlm.nih.gov/pubmed/20392245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05307.x
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