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Alteration of Notch signaling in skeletal development and disease

Notch signaling is an evolutionarily conserved mechanism for specifying and regulating organogenesis and tissue renewal. Human and mouse genetic studies have demonstrated mutations in many components of the Notch signaling pathway that cause skeletal patterning defects. More recently, the in vivo ef...

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Autors principals: Tao, Jianning, Chen, Shan, Lee, Brendan
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952341/
https://ncbi.nlm.nih.gov/pubmed/20392245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05307.x
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