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Roles of yeast DNA polymerases δ and ζ and of Rev1 in the bypass of abasic sites
Abasic (AP) sites are one of the most frequently formed lesions in DNA, and they present a strong block to continued synthesis by the replicative DNA machinery. Here we show efficient bypass of an AP site by the combined action of yeast DNA polymerases δ and ζ. In this reaction, Polδ inserts an A nu...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312678/ https://ncbi.nlm.nih.gov/pubmed/11316789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.882301 |
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