The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes
Histone deacetylation plays an important role in methylated DNA silencing. Recent studies indicated that the methyl-CpG-binding protein, MBD2, is a component of the MeCP1 histone deacetylase complex. Interestingly, MBD2 is able to recruit the nucleosome remodeling and histone deacetylase, NuRD, to m...
Spremljeno u:
| Izdano u: | Genes Dev |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2001
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11297506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.876201 |
| Oznake: |
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|
