The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes

Histone deacetylation plays an important role in methylated DNA silencing. Recent studies indicated that the methyl-CpG-binding protein, MBD2, is a component of the MeCP1 histone deacetylase complex. Interestingly, MBD2 is able to recruit the nucleosome remodeling and histone deacetylase, NuRD, to m...

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Pubblicato in:	Genes Dev
Autori principali:	Feng, Qin, Zhang, Yi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2001
Soggetti:	Research Communication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11297506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.876201
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