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The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes

Histone deacetylation plays an important role in methylated DNA silencing. Recent studies indicated that the methyl-CpG-binding protein, MBD2, is a component of the MeCP1 histone deacetylase complex. Interestingly, MBD2 is able to recruit the nucleosome remodeling and histone deacetylase, NuRD, to m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Feng, Qin, Zhang, Yi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2001
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC312663/
https://ncbi.nlm.nih.gov/pubmed/11297506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.876201
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