NS4B Self-Interaction through Conserved C-Terminal Elements Is Required for the Establishment of Functional Hepatitis C Virus Replication Complexes

Hepatitis C virus (HCV) is an important human pathogen, persistently infecting more than 170 million individuals worldwide. Studies of the HCV life cycle have become possible with the development of cell culture systems supporting the replication of viral RNA and the production of infectious virus....

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Main Authors: Paul, David, Romero-Brey, Inés, Gouttenoire, Jérôme, Stoitsova, Savina, Krijnse-Locker, Jacomine, Moradpour, Darius, Bartenschlager, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126587/
https://ncbi.nlm.nih.gov/pubmed/21543474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00502-11
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