Binding Interactions between Soluble HIV Envelope Glycoproteins and Quaternary-Structure-Specific Monoclonal Antibodies PG9 and PG16

PG9 and PG16 are antibodies isolated from a subject infected with HIV-1 and display broad anti-HIV neutralizing activities. They recognize overlapping epitopes, which are preferentially expressed on the membrane-anchored trimeric form of the HIV envelope glycoprotein (Env). PG9 and PG16 were reporte...

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Главные авторы: Davenport, Thaddeus M., Friend, Della, Ellingson, Katharine, Xu, Hengyu, Caldwell, Zachary, Sellhorn, George, Kraft, Zane, Strong, Roland K., Stamatatos, Leonidas
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2011
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126577/
https://ncbi.nlm.nih.gov/pubmed/21543501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00411-11
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