Regulation of mTORC1 Complex Assembly and Signaling by GRp58/ERp57

The mammalian target of rapamycin (mTOR) regulates cell growth and survival via two different multiprotein complexes, mTORC1 and mTORC2. The assembly of these serine-threonine kinase multiprotein complexes occurs via poorly understood molecular mechanisms. Here, we demonstrate that GRp58/ERp57 regul...

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Main Authors: Ramírez-Rangel, Iliana, Bracho-Valdés, Ismael, Vázquez-Macías, Aleida, Carretero-Ortega, Jorge, Reyes-Cruz, Guadalupe, Vázquez-Prado, José
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126338/
https://ncbi.nlm.nih.gov/pubmed/21321085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00824-10
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