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Epigenetic Regulation of Transcription and Virulence in Trypanosoma cruzi by O-Linked Thymine Glucosylation of DNA

Unlike other eukaryotes, the protein-coding genes of Trypanosoma cruzi are arranged in large polycistronic gene clusters transcribed by polymerase II (Pol II). Thus, it is thought that trypanosomes rely solely on posttranscriptional processes to regulate gene expression. Here, we show that the gluco...

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Bibliografiske detaljer
Main Authors: Ekanayake, Dilrukshi K., Minning, Todd, Weatherly, Brent, Gunasekera, Kapila, Nilsson, Daniel, Tarleton, Rick, Ochsenreiter, Torsten, Sabatini, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126337/
https://ncbi.nlm.nih.gov/pubmed/21321080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01277-10
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