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Epigenetic Regulation of Transcription and Virulence in Trypanosoma cruzi by O-Linked Thymine Glucosylation of DNA

Unlike other eukaryotes, the protein-coding genes of Trypanosoma cruzi are arranged in large polycistronic gene clusters transcribed by polymerase II (Pol II). Thus, it is thought that trypanosomes rely solely on posttranscriptional processes to regulate gene expression. Here, we show that the gluco...

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Detalhes bibliográficos
Main Authors: Ekanayake, Dilrukshi K., Minning, Todd, Weatherly, Brent, Gunasekera, Kapila, Nilsson, Daniel, Tarleton, Rick, Ochsenreiter, Torsten, Sabatini, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126337/
https://ncbi.nlm.nih.gov/pubmed/21321080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01277-10
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