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Oncolytic Specificity of Newcastle Disease Virus Is Mediated by Selectivity for Apoptosis-Resistant Cells

Newcastle disease virus (NDV) is a negative-sense RNA virus that has been shown to possess oncolytic activity. NDV's selective replication in tumor cells has been previously suggested to be due to the lack of a proper antiviral response in these cells. Here we demonstrate that NDV possesses onc...

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Autors principals: Mansour, Mena, Palese, Peter, Zamarin, Dmitriy
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126310/
https://ncbi.nlm.nih.gov/pubmed/21471241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01537-10
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