Significant Protection against High-Dose Simian Immunodeficiency Virus Challenge Conferred by a New Prime-Boost Vaccine Regimen

We constructed vaccine vectors based on live recombinant vesicular stomatitis virus (VSV) and a Semliki Forest virus (SFV) replicon (SFVG) that propagates through expression of the VSV glycoprotein (G). These vectors expressing simian immunodeficiency virus (SIV) Gag and Env proteins were used to va...

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Detalhes bibliográficos
Main Authors: Schell, John B., Rose, Nina F., Bahl, Kapil, Diller, Kathryn, Buonocore, Linda, Hunter, Meredith, Marx, Preston A., Gambhira, Ratish, Tang, Haili, Montefiori, David C., Johnson, Welkin E., Rose, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126289/
https://ncbi.nlm.nih.gov/pubmed/21490100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00342-11
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