Recombinant Adenovirus Serotype 26 (Ad26) and Ad35 Vaccine Vectors Bypass Immunity to Ad5 and Protect Nonhuman Primates against Ebolavirus Challenge

The use of adenoviruses (Ad) as vaccine vectors against a variety of pathogens has demonstrated their capacity to elicit strong antibody and cell-mediated immune responses. Adenovirus serotype C vectors, such as Ad serotype 5 (Ad5), expressing Ebolavirus (EBOV) glycoprotein (GP), protect completely...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Geisbert, Thomas W., Bailey, Michael, Hensley, Lisa, Asiedu, Clement, Geisbert, Joan, Stanley, Daphne, Honko, Anna, Johnson, Joshua, Mulangu, Sabue, Pau, Maria Grazia, Custers, Jerome, Vellinga, Jort, Hendriks, Jenny, Jahrling, Peter, Roederer, Mario, Goudsmit, Jaap, Koup, Richard, Sullivan, Nancy J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2011
Θέματα:
Pathogenesis and Immunity
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126236/
https://ncbi.nlm.nih.gov/pubmed/21325402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02407-10
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