The Polypyrimidine Tract-Binding Protein Affects Coronavirus RNA Accumulation Levels and Relocalizes Viral RNAs to Novel Cytoplasmic Domains Different from Replication-Transcription Sites

The coronavirus (CoV) discontinuous transcription mechanism is driven by long-distance RNA-RNA interactions between transcription-regulating sequences (TRSs) located at the 5′ terminal leader (TRS-L) and also preceding each mRNA-coding sequence (TRS-B). The contribution of host cell proteins to CoV...

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Main Authors: Sola, Isabel, Galán, Carmen, Mateos-Gómez, Pedro A., Palacio, Lorena, Zúñiga, Sonia, Cruz, Jazmina L., Almazán, Fernando, Enjuanes, Luis
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126201/
https://ncbi.nlm.nih.gov/pubmed/21411518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00195-11
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