A Point Mutation within the Replicase Gene Differentially Affects Coronavirus Genome versus Minigenome Replication

During the construction of the transmissible gastroenteritis virus (TGEV) full-length cDNA clone, a point mutation at position 637 that was present in the defective minigenome DI-C was maintained as a genetic marker. Sequence analysis of the recovered viruses showed a reversion at this position to t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Galán, Carmen, Enjuanes, Luis, Almazán, Fernando
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2005
Gaiak:
Genome Replication and Regulation of Viral Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316003/
https://ncbi.nlm.nih.gov/pubmed/16306572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15016-15026.2005
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