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A Point Mutation within the Replicase Gene Differentially Affects Coronavirus Genome versus Minigenome Replication
During the construction of the transmissible gastroenteritis virus (TGEV) full-length cDNA clone, a point mutation at position 637 that was present in the defective minigenome DI-C was maintained as a genetic marker. Sequence analysis of the recovered viruses showed a reversion at this position to t...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316003/ https://ncbi.nlm.nih.gov/pubmed/16306572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15016-15026.2005 |
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