Long-Distance RNA-RNA Interactions in the Coronavirus Genome Form High-Order Structures Promoting Discontinuous RNA Synthesis during Transcription

Coronavirus (CoV) transcription requires a high-frequency recombination process that links newly synthesized minus-strand subgenomic RNA copies to the leader region, which is present only once, at the 5′ end of the genome. This discontinuous RNA synthesis step is based on the complementarity between...

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Bibliographic Details
Main Authors: Mateos-Gomez, Pedro A., Morales, Lucia, Zuñiga, Sonia, Enjuanes, Luis, Sola, Isabel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536410/
https://ncbi.nlm.nih.gov/pubmed/23055566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01782-12
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