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Assembly of Helper-Dependent Adenovirus DNA into Chromatin Promotes Efficient Gene Expression
Helper-dependent adenovirus (hdAd) vectors have shown tremendous potential in animal models of human disease in numerous preclinical studies. Expression of a therapeutic transgene can be maintained for several years after a single administration of the hdAd vector. However, despite the long-term per...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126148/ https://ncbi.nlm.nih.gov/pubmed/21307207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01787-10 |
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