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Key Genomic Changes Necessary for an In Vivo Lethal Mouse Marburgvirus Variant Selection Process

Marburgvirus (MARV) infections are generally lethal in humans and nonhuman primates but require in vivo lethal mouse variant selection by the serial transfer (passage) of the nonlethal virus into naïve mice to propagate a lethal infection. The passage of progenitor (wild-type) MARV or Ravn virus (RA...

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Detalhes bibliográficos
Main Authors: Lofts, Loreen L., Wells, Jay B., Bavari, Sina, Warfield, Kelly L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126133/
https://ncbi.nlm.nih.gov/pubmed/21289122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02372-10
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