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Key Genomic Changes Necessary for an In Vivo Lethal Mouse Marburgvirus Variant Selection Process
Marburgvirus (MARV) infections are generally lethal in humans and nonhuman primates but require in vivo lethal mouse variant selection by the serial transfer (passage) of the nonlethal virus into naïve mice to propagate a lethal infection. The passage of progenitor (wild-type) MARV or Ravn virus (RA...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126133/ https://ncbi.nlm.nih.gov/pubmed/21289122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02372-10 |
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