Development of a model for marburgvirus based on severe-combined immunodeficiency mice

The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever. Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a mouse-adapted MARV model. Previously, a uniformly lethal EBOV-Zaire mouse-adapted virus was developed by pe...

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Main Authors: Warfield, Kelly L, Alves, Derron A, Bradfute, Steven B, Reed, Daniel K, VanTongeren, Sean, Kalina, Warren V, Olinger, Gene G, Bavari, Sina
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2164958/
https://ncbi.nlm.nih.gov/pubmed/17961252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-108
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