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Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival
Mutant src(−/−) mice have osteopetrosis resulting from defective osteoclasts, the cells that resorb bone. However, signaling pathways involving Src family members in osteoclasts remain unclear. We demonstrate that expression of a truncated Src molecule, Src251, lacking the kinase domain, induces ost...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312612/ https://ncbi.nlm.nih.gov/pubmed/11157779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.840301 |
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