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Domain structure, localization, and function of DNA polymerase η, defective in xeroderma pigmentosum variant cells
DNA polymerase η carries out translesion synthesis past UV photoproducts and is deficient in xeroderma pigmentosum (XP) variants. We report that polη is mostly localized uniformly in the nucleus but is associated with replication foci during S phase. Following treatment of cells with UV irradiation...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Cold Spring Harbor Laboratory Press
2001
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312610/ https://ncbi.nlm.nih.gov/pubmed/11157773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.187501 |
| Tagiau: |
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