The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures

The active derivative of vitamin A, retinoic acid (RA), is essential for normal embryonic development. The spatio-temporal distribution of embryonic RA results from regulated expression of RA-synthesizing retinaldehyde dehydrogenases and RA-metabolizing cytochrome P450s (CYP26). Excess RA administra...

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Bibliographic Details
Main Authors: Abu-Abed, Suzan, Dollé, Pascal, Metzger, Daniel, Beckett, Barbara, Chambon, Pierre, Petkovich, Martin
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2001
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC312609/
https://ncbi.nlm.nih.gov/pubmed/11157778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.855001
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