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The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures

The active derivative of vitamin A, retinoic acid (RA), is essential for normal embryonic development. The spatio-temporal distribution of embryonic RA results from regulated expression of RA-synthesizing retinaldehyde dehydrogenases and RA-metabolizing cytochrome P450s (CYP26). Excess RA administra...

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Publicat a:Genes Dev
Autors principals: Abu-Abed, Suzan, Dollé, Pascal, Metzger, Daniel, Beckett, Barbara, Chambon, Pierre, Petkovich, Martin
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.855001
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