The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures

The active derivative of vitamin A, retinoic acid (RA), is essential for normal embryonic development. The spatio-temporal distribution of embryonic RA results from regulated expression of RA-synthesizing retinaldehyde dehydrogenases and RA-metabolizing cytochrome P450s (CYP26). Excess RA administra...

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Detalhes bibliográficos
Main Authors: Abu-Abed, Suzan, Dollé, Pascal, Metzger, Daniel, Beckett, Barbara, Chambon, Pierre, Petkovich, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312609/
https://ncbi.nlm.nih.gov/pubmed/11157778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.855001
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