GIT1 is a novel MEK1–ERK1/2 scaffold that localizes to focal adhesions

Cell polarity is critical for cell migration and requires localized signal transduction in subcellular domains. Recent evidence demonstrates that activation of ERK1/2 (extracellular-signal-regulated kinase 1/2) in focal adhesions is essential for cell migration. GIT1 (G-protein-coupled receptor kina...

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Hlavní autoři: Zhang, Ning, Cai, Weihua, Yin, Guoyong, Nagel, David J., Berk, Bradford C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125965/
https://ncbi.nlm.nih.gov/pubmed/19947948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CBI20090016
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