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An epidermal growth factor (EGF) -dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor

G-protein coupled receptor (GPCR) kinase-2 interacting protein 1 (GIT1) is a multifunctional scaffolding protein that regulates epidermal growth factor receptor (EGFR) signaling pathways. We demonstrate that GIT1 interacts with sorting nexin 6 (SNX6), a member of the SNX family that increases EGFR t...

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Detalles Bibliográficos
Main Authors: Cavet, Megan E., Pang, Jinjiang, Yin, Guoyong, Berk, Bradford C.
Formato: Artigo
Idioma:Inglês
Publicado: The Federation of American Societies for Experimental Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537429/
https://ncbi.nlm.nih.gov/pubmed/18523162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-094086
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