In Vivo Regulation of the Vi Antigen in Salmonella and Induction of Immune Responses with an In Vivo-Inducible Promoter

Salmonella enterica serovar Typhi, the agent of typhoid fever in humans, expresses the surface Vi polysaccharide antigen that contributes to virulence. However, Vi expression can also be detrimental to some key steps of S. Typhi infectivity, for example, invasion, and Vi is the target of protective...

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Detalhes bibliográficos
Main Authors: Janis, Carole, Grant, Andrew J., McKinley, Trevelyan J., Morgan, Fiona J. E., John, Victoria F., Houghton, Jenny, Kingsley, Robert A., Dougan, Gordon, Mastroeni, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125847/
https://ncbi.nlm.nih.gov/pubmed/21402763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01265-10
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