Immunization with Bacillus Spores Expressing Toxin A Peptide Repeats Protects against Infection with Clostridium difficile Strains Producing Toxins A and B

Clostridium difficile is a leading cause of nosocomial infection in the developed world. Two toxins, A and B, produced by most strains of C. difficile are implicated as virulence factors, yet only recently has the requirement of these for infection been investigated by genetic manipulation. Current...

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Detalhes bibliográficos
Main Authors: Permpoonpattana, Patima, Hong, Huynh A., Phetcharaburanin, Jutarop, Huang, Jen-Min, Cook, Jenny, Fairweather, Neil F., Cutting, Simon M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125831/
https://ncbi.nlm.nih.gov/pubmed/21482682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00130-11
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