Bacterial Spores as Vaccine Vehicles

For the first time, bacterial spores have been evaluated as vaccine vehicles. Bacillus subtilis spores displaying the tetanus toxin fragment C (TTFC) antigen were used for oral and intranasal immunization and were shown to generate mucosal and systemic responses in a murine model. TTFC-specific immu...

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Detalhes bibliográficos
Main Authors: Duc, Le H., Hong, Huynh A., Fairweather, Neil, Ricca, Ezio, Cutting, Simon M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153275/
https://ncbi.nlm.nih.gov/pubmed/12704155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2810-2818.2003
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