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Recombinant Bacillus subtilis Expressing the Clostridium perfringens Alpha Toxoid Is a Candidate Orally Delivered Vaccine against Necrotic Enteritis

Recombinant Bacillus subtilis endospores have been used to vaccinate against tetanus and anthrax. In this work, we have developed spores that could be used to vaccinate against Clostridium perfringens alpha toxin and that could be used to protect against gas gangrene in humans and necrotic enteritis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoang, Tran H., Hong, Huynh A., Clark, Graeme C., Titball, Richard W., Cutting, Simon M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573343/
https://ncbi.nlm.nih.gov/pubmed/18779344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00686-08
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