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Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest

Members of the Gadd45 family play central roles in the cellular response to genotoxic stress, and have been implicated in several human cancers including hepatocellular carcinomas. Chronic infection by hepatitis C virus (HCV) is a major risk factor for the onset and development of primary hepatocell...

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Detalhes bibliográficos
Main Authors: Higgs, Martin R., Lerat, Hervé, Pawlotsky, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125696/
https://ncbi.nlm.nih.gov/pubmed/20530689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4554
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