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Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest
Members of the Gadd45 family play central roles in the cellular response to genotoxic stress, and have been implicated in several human cancers including hepatocellular carcinomas. Chronic infection by hepatitis C virus (HCV) is a major risk factor for the onset and development of primary hepatocell...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Association for Cancer Research
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125696/ https://ncbi.nlm.nih.gov/pubmed/20530689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4554 |
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