Regulation of Hepatitis C Virus Replication by Nuclear Translocation of Nonstructural 5A Protein and Transcriptional Activation of Host Genes

Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is involved in regulating viral replication through its direct interaction with the HCV RNA-dependent RNA polymerase. NS5A also alters infected cell metabolism through complex interactions with numerous host cell proteins. NS5A has furthermore...

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Bibliografiska uppgifter
Huvudupphovsmän: Maqbool, Muhammad Ahmad, Imache, Mohamed R., Higgs, Martin R., Carmouse, Sophie, Pawlotsky, Jean-Michel, Lerat, Hervé
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648193/
https://ncbi.nlm.nih.gov/pubmed/23468497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00585-12
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