Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice

Chronic hepatitis C virus (HCV) infection is associated with altered lipid metabolism and hepatocellular steatosis. Virus-induced steatosis is a cytopathic effect of HCV replication. The goal of this study was to examine the mechanisms underlying HCV-induced lipid metabolic defects in a transgenic m...

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Detalhes bibliográficos
Main Authors: Lerat, Hervé, Kammoun, Hélène L., Hainault, Isabelle, Mérour, Emilie, Higgs, Martin R., Callens, Céline, Lemon, Stanley M., Foufelle, Fabienne, Pawlotsky, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785191/
https://ncbi.nlm.nih.gov/pubmed/19808675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019810
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