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Rapid activity-induced transcription of arc and other IEGs relies on poised RNA polymerase II
Transcription of immediate early genes (IEGs) in neurons is exquisitely sensitive to neuronal activity, but the mechanism underlying these early transcription events is largely unknown. We demonstrate that several IEGs such as arc/arg3.1 are poised for near-instantaneous transcription by the stallin...
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Hoofdauteurs: | , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125443/ https://ncbi.nlm.nih.gov/pubmed/21623364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2839 |
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