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Novel cis-regulatory function in ICR-mediated imprinted repression of H19
Expression of coregulated imprinted genes, H19 and Igf2, is monoallelic and parent-of-origin-dependent. Like most imprinted genes, H19 and Igf2 are regulated by a differentially methylated imprinting control region (ICR). CTCF binding sites and DNA methylation at the ICR have previously been identif...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125397/ https://ncbi.nlm.nih.gov/pubmed/21600199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.04.036 |
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