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Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region

Parent-of-origin-specific expression at imprinted genes is regulated by allele-specific DNA methylation at imprinting control regions (ICRs). This mechanism of gene regulation, where one element controls allelic expression of multiple genes, is not fully understood. Furthermore, the mechanism of gen...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Ideraabdullah, Folami Y., Thorvaldsen, Joanne L., Myers, Jennifer A., Bartolomei, Marisa S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222363/
https://ncbi.nlm.nih.gov/pubmed/24990148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu344
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