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Construction of a human chromosome 4 YAC pool and analysis of artificial chromosome stability.

In order to construct a human chromosome 4-specific YAC library, we have utilized pYAC4 and a mouse/human hybrid cell line HA(4)A in which the only human chromosome present is chromosome 4. From this cell line, approximately 8Mb of chromosome 4 have been cloned. The library includes 65 human-specifi...

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Dettagli Bibliografici
Autori principali: Sleister, H M, Mills, K A, Blackwell, S E, Killary, A M, Murray, J C, Malone, R E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC312498/
https://ncbi.nlm.nih.gov/pubmed/1630913
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