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Conformational Changes During the Gating of a Potassium Channel Revealed by Structural Mass Spectrometry
Potassium channels are dynamic proteins that undergo large conformational changes to regulate the flow of K(+) ions across the cell membrane. Understanding the gating mechanism of these channels therefore requires methods for probing channel structure in both their open and closed conformations. Rad...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124773/ https://ncbi.nlm.nih.gov/pubmed/20637420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.04.012 |
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