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An Intronic Mutation is Associated with Prolactinoma in a Young Boy, Decreased Penetrance in his Large Family, and Variable Effects on MEN1 mRNA and Protein

Prolactinomas are rare tumors in prepubertal children. A prolactinoma in a young child may be due to sequence variants in genes that are known to cause these tumors (MEN1, PRKAR1A, AIP). An 11-year-old boy with a macroprolactinoma was treated with cabergoline and the tumor receded. We studied the pa...

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Detaylı Bibliyografya
Asıl Yazarlar: Drori-Herishanu, L., Horvath, A., Nesterova, M., Patronas, Y., Lodish, M., Bimpaki, E., Patronas, N., Agarwal, S., Salvatori, R., Martari, M., Mericq, V., Stratakis, C. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124761/
https://ncbi.nlm.nih.gov/pubmed/19391077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0029-1216358
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