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THE GROWTH HORMONE RECEPTOR (GHR) POLYMORPHISM IN GROWTH-RETARDED CHILDREN WITH CUSHING DISEASE: LACK OF ASSOCIATION WITH GROWTH AND MEASURES OF THE SOMATOTROPIC AXIS

OBJECTIVE: Pediatric Cushing disease (CD) often presents with short stature but we have observed significant inter-individual variability in the growth delay caused by endogenous hypercortisolism. Glucocorticoids cause growth retardation by affecting the growth hormone (GH) – insulin-like growth fac...

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Detalhes bibliográficos
Main Authors: Drori-Herishanu, Limor, Lodish, Maya, Verma, Somya, Bimpaki, Eirini, Keil, Meg F., Horvath, Anelia, Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412355/
https://ncbi.nlm.nih.gov/pubmed/20013551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0029-1242744
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