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Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma?
OBJECTIVE: Recent studies identify aberrant Wnt signaling in scleroderma and pulmonary fibrosis. The aim of present study was to investigate the effect of ectopic Wnt10b expression on skin homeostasis and differentiation in transgenic mice with FABP4-directed Wnt10b expression. METHODS: The expressi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124699/ https://ncbi.nlm.nih.gov/pubmed/21370225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30312 |
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