CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma

Mice subcutaneously injected with bleomycin, in an experimental model of human systemic sclerosis, develop cutaneous and lung fibrosis with autoantibody production. CD19 is a general “rheostat” that defines signaling thresholds critical for humoral immune responses, autoimmunity, and cytokine produc...

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Detalhes bibliográficos
Main Authors: Yoshizaki, Ayumi, Iwata, Yohei, Komura, Kazuhiro, Ogawa, Fumihide, Hara, Toshihide, Muroi, Eiji, Takenaka, Motoi, Shimizu, Kazuhiro, Hasegawa, Minoru, Fujimoto, Manabu, Tedder, Thomas F., Sato, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408424/
https://ncbi.nlm.nih.gov/pubmed/18467694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071049
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