CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma

Mice subcutaneously injected with bleomycin, in an experimental model of human systemic sclerosis, develop cutaneous and lung fibrosis with autoantibody production. CD19 is a general “rheostat” that defines signaling thresholds critical for humoral immune responses, autoimmunity, and cytokine produc...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Yoshizaki, Ayumi, Iwata, Yohei, Komura, Kazuhiro, Ogawa, Fumihide, Hara, Toshihide, Muroi, Eiji, Takenaka, Motoi, Shimizu, Kazuhiro, Hasegawa, Minoru, Fujimoto, Manabu, Tedder, Thomas F., Sato, Shinichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2008
Soggetti:
Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408424/
https://ncbi.nlm.nih.gov/pubmed/18467694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071049
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi