Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling

Rolling leukocytes are exposed to different adhesion molecules and chemokines. Neutrophil rolling on E-selectin induces integrin α(L)β(2)-mediated slow rolling on intercellular adhesion molecule-1 by activating a phospholipase C (PLC)γ2- and a separate phosphoinositide-3-kinase (PI3K)γ-dependent pat...

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Main Authors: Stadtmann, Anika, Brinkhaus, Laura, Mueller, Helena, Rossaint, Jan, Bolomini-Vittori, Matteo, Bergmeier, Wolfgang, Van Aken, Hugo, Wagner, Denisa D., Laudanna, Carlo, Ley, Klaus, Zarbock, Alexander
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124568/
https://ncbi.nlm.nih.gov/pubmed/21480213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041196
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