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The role of IκB kinase complex in the neurobiology of Huntington's disease

The IκB kinase β (IKKβ) is a prominent regulator of neuroinflammation, which is implicated in the pathogenesis of Huntington's disease (HD). Inflammatory mediators accumulate in the serum and CNS of premanifest and manifest HD patients, and cytokine levels correlate with disease progression. IK...

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Bibliografske podrobnosti
Main Authors: Khoshnan, Ali, Patterson, Paul H.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124142/
https://ncbi.nlm.nih.gov/pubmed/21554955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.04.015
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