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The role of IκB kinase complex in the neurobiology of Huntington's disease

The IκB kinase β (IKKβ) is a prominent regulator of neuroinflammation, which is implicated in the pathogenesis of Huntington's disease (HD). Inflammatory mediators accumulate in the serum and CNS of premanifest and manifest HD patients, and cytokine levels correlate with disease progression. IK...

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Detaylı Bibliyografya
Asıl Yazarlar: Khoshnan, Ali, Patterson, Paul H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124142/
https://ncbi.nlm.nih.gov/pubmed/21554955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.04.015
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