Dysregulation of the Intrarenal Vitamin D Endocytic Pathway in a Nephropathy-Prone Mouse Model of Type 1 Diabetes

Microalbuminuria in humans with Type 1 diabetes (T1D) is associated with increased urinary excretion of megalin, as well as many megalin ligands, including vitamin-D-binding protein (VDBP). We examined the DBA/2J diabetic mouse, nephropathy prone model, to determine if megalin and VDBP excretion coi...

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Hlavní autoři: Fowlkes, John L., Bunn, R. Clay, Cockrell, Gael E., Clark, Lindsey M., Wahl, Elizabeth C., Lumpkin, Charles K., Thrailkill, Kathryn M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123992/
https://ncbi.nlm.nih.gov/pubmed/21747824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/269378
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