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Mitochondrial Energetics, pH Regulation, and Ion Dynamics: A Computational-Experimental Approach
We developed a computational model of mitochondrial energetics that includes Ca(2+), proton, Na(+), and phosphate dynamics. The model accounts for distinct respiratory fluxes from substrates of complex I and complex II, pH effects on equilibrium constants and enzyme kinetics, and the acid-base equil...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123977/ https://ncbi.nlm.nih.gov/pubmed/21689522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.027 |
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