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DNA synthesis blocking lesions induced by singlet oxygen are targeted to deoxyguanosines.

In vitro DNA synthesis on single stranded templates damaged by singlet oxygen was investigated in the supF tRNA gene sequence, using several DNA polymerases. Singlet oxygen was generated by the thermal decomposition of the water soluble with the endoperoxide of disodium 3,3'-(1,4-naphthylidene)...

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Detalhes bibliográficos
Main Authors: Ribeiro, D T, Bourre, F, Sarasin, A, Di Mascio, P, Menck, C F
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312380/
https://ncbi.nlm.nih.gov/pubmed/1375992
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